Manipulation of microbial gene essentiality in Pseudomonas aeruginosa as the new reaffirmation for novel therapeutic development. Declaration   The work presented in this thesis is entirely my own, except where I have either acknowledged help from a known person or given a publication reference. Abstract   Originally the genus Pseudomonas comprised of non-fermentative  bacteria that were classified by their morphological similarity. The species was described as pseudomonas  due to common cell pair arrangement resembling a singular cell (appendix Figure 1). However due to the controversy surrounding this genera, a vast amount of changes have been done in recent years. Regardless of the changes to the genera currently the most clinically significant isolate is Pseudomonas aeruginosa (PA). PA contains broad environmental distribution and is efficient in adapting and regulating phenotype based on the site of infection. This adaptability has facilitated an emergence of multi-drug resistant strains creating a dire necessity for new treatments to combat the continuous rise of antimicrobial resistance. However, currently, there is a significant advancement gap with few novel antimicrobial frameworks introduced in the current clinical practice. To…

Tips and Strategies for Moving During the Winter Season After a long summer, the season of snow is finally here! As much as we all love the snow and the winter breeze, sometimes these very things become a hassle in our daily routine. How so, you may ask! That is because what if you have to move houses in the middle of winter? Yes, that might be a small reason for the trouble. We bring to you a few tips that will help you move houses quickly with all the comfort and warmth you require. While moving long distance in winter, there are some essential things that you should keep in mind. Here are a few tips that will help you through the long task: Do Not Forget to Confirm all the Important Details with your Movers If you have waited all this while for moving in the winter, then you will continue to agree that it is a good idea. Moving in snowy weather is a good deal because the moving companies usually have their off-season at this time.…

The zika outbreak in Brazil The zika outbreak occurred in 2015-2016. The virus was first discovered in Kampala, Uganda, in 1947. A mosquito of the Aedes family carries it. By the mosquito, virginal, anal thor oral sex. The disease has mild symptoms such as flu symptoms red rashes and can be mistaken for chikungunya and dengue fever, which are transmitted by the same means. The disease spread in Brazil and other parts of southern and northern America. The epidemic had diverse effects on population health. It was found to affect women mostly and the pregnant ones at most. It led to newborn having microcephaly and other neurological impairments. As a result of increasing cases, Brazil declared a national public emergency in November 2015. The world health organization followed announcing the disease as a pandemic three months later. The rapid spread of the disease was as a result of a susceptible population, the climate conditions were offered favorable breeding grounds for mosquitos vectors, and the vast movements of people from time to time, causing the disease to spread even further. The…

potential and the real threats to Unilever UK The following is an analysis of the potential and the real threats to Unilever UK in terms of their many brands and their reach across the globe. Important to note about the organizations herein is that all of them are multinational companies because as Unilever is structured, its competition can only be scaled on a global weight because of the global reach that Unilever has. The brands must be operating in the many regions that Unilever has based its products. Additionally, there is another peculiarity to determining the companies that present competition to Unilever based on the types of products and brands. Unilever has over 400 brands and therefore, a company that presents competition to the company must be able to compete with various brands that are owned by Unilever. By virtue of the significant brand reach and numerous brands, it is impossible for a company that does not have several products and a range of competitive brands to compete with the massive reach of Unilever products. Therefore, this guides the choice…

Resume paper Name Street Address City Phone Number Email Address| LinkedIn URL   Professional Profile Registered nurse with experience in advancing quality patient care in the surgical and intensive care unit (ICU) Dedicated student in nursing and regularly commended for delivering patient-oriented and critical care to patients, coupled with compassion for recuperating patients and a friendly attitude Presents as a highly organized and skilled individual who exhibits excellent written and verbal communication skills Displays commitment in utilizing both academic and professional knowledge towards the fulfilment of the company’s mission and vision Strong leadership skills to work under pressure in a fast-paced environment, radiate positivity, and guide nursing teams to attain patient care goals Passion and devotion to helping others while utilizing my skills Ability to make swift and accurate decisions in emergency incidences Makes clinical judgments based on standardized procedures, health care plans and scientific knowledge Basic Life Support (BLS) and Advanced Cardiac Life Support (ACLS) certifications that streamline my focus in harnessing expertise and innovations in delivering cardiac care, and reduce mortality associated with cardiac arrests An active member…

COVID-19 Before it was announced on March 11th 2020 by the World Health Organization (WHO), the outbreak of COVID-19 was termed as an epidemic. That is because it had spread to many communities and individuals at the same time. After the announcement, it was termed as a pandemic which meant that the disease was now spreading worldwide at an alarming rate. Through the announcement, WHO was recognizing the inaction and severity and the increasing amounts of deaths and affected countries and its potential to infect more countries. Therefore, it is essential that every country focus on people, preparedness, political leadership, prevention and public health. COVID-19 has been acknowledged that it is the first one to have been caused by a coronavirus. This paper will discuss the COVID-19 disease, examining some of the reasons why it affects other individuals more than others. It will discuss its genetics and other factors that make it spread rapidly across that world. COVID-19 (coronavirus disease) is a contagious illness resulting from coronavirus, which is a severe acute respiratory syndrome. Individuals having the virus may show…

top 10 best baby bouncers and toddler rockers according to moms worldwide For new moms, nothing is more precious than some hands-free time. Baby bouncers allow you to keep your child entertained, safe and even nudges the young ones off to sleep while you get on with other chores. Some of these baby bouncers are suitable from birth, while others are simplistic chairs that keep infants secure while giving them a good bounce if they want to play and exercise. Other high-end models are even more elaborate, complete with built-in rocking motions, vibrations, and all sorts of other entertainment features. Enough chit chat, we know your baby is keeping you thoroughly busy. That’s why we’ve compiled a list of the top 10 best baby bouncers and toddler rockers according to moms worldwide. Contents Disney Baby Winnie The Pooh Bouncer Fisher-Price Deluxe Rock ‘n Play Moonlight Meadow Sleeper Graco DuetConnect LX Swing and Baby Bouncers Ingenuity SmartBounce Automatic Ridgedale Bouncer Fisher-Price Rock ‘n Play Luminosity Sleeper Bright Starts Playful Pinwheels Bouncer Fisher-Price Baby’s Geo Meadow Bouncer Fisher-Price Infant To Toddler Dark…

Domestic Violence among African American Summary The focus of this essay is to look into domestic violence among African Americans. African Americans are descendants of enslaved Africans currently living in the United States. The article looks into three key aspects. First, the causes of domestic violence are highlighted. Second, the consequences are discussed. Lastly, measures to mitigate domestic violence in African American families are proposed. These three aspects provide in-depth insight into the issue. Introduction Domestic violence is a social vice affecting a large number of families globally. African American families in the United States are of no exception.  Domestic violence has been broadly described as any violent or aggressive behavior within a home that involves abuse from a spouse of a partner (United Nations, 2016). Women are the most often victims of domestic violence in the subject families. They are of Victims Intimate Partner Violence (IPV), which includes acts of physical abuse, sexual violence, emotional violence, and controlling behavior (KO, 2015).  Regardless of the sensitivity and significance of the subject issue, little attention has been paid to it. Understanding…

 Pillars of Promotion What is one thing which bothers you most after you got a good job? Getting promoted or getting raise, right? You are working your heart out in the office but is yet to unlock the door to promotion. Our expectation drives us naturally towards a better and more secure future. But a current professional is far more challenging, competitive than ever. You might get confused in the rat race to succeed. Many employees are indulged in job dissatisfaction due to lousy boss, lacking quality work, etc. Employees and employers are engaged in a fundamental conflict of interest and tug of war for money, time, and effort. The employers aim to acquire a high quantity of quality work with a minimal expense possible. Employees, on the other hand, seeks a secure professional life with a balance of work-life. It is time that we help you find the hacks which can help you unlock the key to promotion. You will be able to apply the hacks easily without hampering any ethics and employee-employer relation. The hacks are simple ideas…

  Elder Abuse Legal Issues Existing Issue Abuse, in this case, refers to any form of action taken against an older person that is unlawful. It is important to note that some acts may not necessarily be unlawful even though deemed unethical. Abuse involves psychological, emotional, and physical abuse. Abused older adults are more likely to suffer bodily injury and death (Stiegel, 2014). Neglect is a form of abuse that affects the individual emotionally and physically and can result in a financial drain. Capacity, which involves the physical and mental function of the elderly (Center for Elders and the Courts, n.d.) plays a significant role as concerns neglect. Importance of Neglect Issue to Oregon’s Elderly Oregon understands the issue of elder abuse and, as such, has a law that seeks to protect the older population. The Older Americans Act is keen on freedom, community participation, independence, and protection against neglect and exploitation (“State of Oregon: SUA – Elderly and Vulnerable Adult Rights and Abuse Prevention”, 2020). In this regard, neglect of the elderly population is not only unethical but unlawful. Negligence…