Top Ten Signs That It Is Time To Replace Your Roof The roof forms a very critical part of the house, and at all times, it should be in perfect condition. Having an elegant roof fixed rightly above your head gives you a warm and cozy environment. If the roof is too old, there might be a future problem, even if it looks good from the outside. Below are the top ten signs that it is time to replace your roof. Curling Shingles Shingles tend to curl when there is cupping or when they are clawing. The former happens when the edges of the roof have turned upwards. The latter occurs when the sides of the roof remain flat, whereas its middle parts begin to come up. These two signs indicate weathering and could lead to potential leaks.  When this becomes a clear sign, you do not have much time remaining. Look at the degree of the curling shingles and plan to change your roof. Missing Shingles If you notice some missing shingles on your roof, continue making repairs until…

Ambulatory Oncology Chair Utilisation in Australia Background Over the past decades, cancer has increasingly become one of the leading causes of death worldwide (Nagai & Kim, 2017). In 2018, cancer accounted for more than nine million deaths worldwide (Bray et al., 2018). Scientific evidence suggests that cancer is a group of severe health conditions that affect the quality of life across all human societies (Ko et al., 2014). It begins with genetic changes that lead to abnormal and uncontrollable growth of cells, which lead to the formation of a tumour. Usually, these tumours are either malignant or benign and can start in ant tissue or organ of the body. As the current burden of cancer continues to grow exponentially around the globe, research shows that lifestyle factors such as tobacco smoking and change in diet patterns, among other environmental factors are responsible for the development of cancer (Patel et al., 2018). Currently, health care systems have been strained this phenomenon, while communities have been experiencing emotional, physical, and financial strain. Cancer has been proven to be a significant factor in…

All for Nothing  More often than not, we are usually in search of a hero to get us out of a horrid situation physically, emotionally, or spiritually. It is human nature to seek comfort or an escape to a place of peace. However, life has a different view on how things run. Reality is sometimes harsh and unbearable for a majority. This fact explains why people constantly fall into a depression to the extent of having suicidal tendencies, it explains why people give up hope. Despite the constant challenges to which we are exposed, there is literature. This is a category in art that has opened people more to the nature of the world. It is a space through which people relate more to their situations and find a way to handle their issues once they are in a fix. The most respectable element of literature is its capacity to communicate issues that affect the community even when the content is pure non-fiction. The book “All for Nothing” by Walter Kempowski is one of the most popular pieces of literature.…

The cost variability of a medicine company The cost variability of a medicine company depends on the target market and production. Most of the time, costs remain the same in developed countries. On the other hand, cost varies in developing countries based on the economic capacity of the country and the buying efficiency of the target audience. Brand drug companies like Ambien, Ativan, Diabeta, and Hytrin use to sell drugs at a comparatively lower price in developing countries like India, China, and Kenya. Reasons to sell medicines at a more moderate rate are the following: Low buying capability Lower per capita income than the developed nations Economic instability Inconsistency in the economic policies Cost remains fixed in developed countries like the USA because of a steady buying power. Reasons for keeping price attached in countries like the USA are mentioned below High buying capability Economic stability Higher per capita income The cost variability and cost fixing strategies are developed using fixed and variable cost analysis. Here, the parameter of fixing cost for brand drug is financial stability, and the reason…

Black men and public space In US history, African-Americans have borne the brunt of well calculate prejudice and stereotyping emanating from collective labeling and perception that all of them are thugs. Such belief is deeply entrenched in American society to the extent that even law enforcement is not impartial but instead embarks on ethnic profiling of the black Americans in the community. Through the experience of Staples conveys a disturbing scenario that subjected the black people to humiliation, vulnerable, and condemned them to eternal suspicion and mistrust in American society. Owing to the deprivation and discrimination along the racial lines, the author notes that the African Americans got pushed to the periphery of oblivion, an aspect that prompted them to embark on crime to fend for themselves. However, the development meant that all the black men were labeled as thugs regardless of their education status or background. In the eyes of most of the white majority and the police enforcement, every black person remained a thug and a security threat until proved otherwise.  Thus, associating the black man with a…

The Ebola Virus The Ebola virus (EVD) is a hemorrhagic fever that affects human beings and other primates (Baseler et al., 2017). This fever is caused by the Ebola viruses and is fatal once it remains untreated. The Ebola virus can receive treatment through vaccines which are still under development. Severe cases of the infection have been experienced in Guinea and the Democratic Republic of Congo in recent years. Its symptoms begin between two and three weeks after the virus has been contacted in human beings (Baseler et al., 2017). In a detailed analysis done in this paper, the symptoms, transmission, diagnosis, prevention and control, among other facts about the virus are discussed in details. Signs and Symptoms In the early stages of the Ebola fever, it can feel like the common flu. The incubation time of the virus which is the period from its contraction to the time of the onset of its symptoms is from two to 21 days which can equally be translated to three weeks (Baseler et al., 2017). An infected person can show some sudden…

Best board games of all time There is no better way to relax and enjoy more abundant leisure time than while playing board games with family and friends. Board games are a perfect way to spend your free time and engage your minds. The games are played with colleagues, friends or family members. There are a variety of board games from scrabble, chess, and many others. Board games can be based on chance, strategy, or the combination of the two players to achieve before their competitors. Gaming can be an epicenter of entertainment among the adults, and a platform to aid the development of literacy competence as well as provide moral guidance. This article will discuss the best board games of all time that one can engage in. Chess Chess needs two players at a given time of play. It is purely a strategical board game normally played on a chessboard. The board has to be checked with 64 squares arranged in an eighty-eight grid. Chess dates back its origin from India during the Gupta Empire. Ideally, the 64 square…

The Color of Egg Produced by Different Chicken Breeds Different breeds of chicken have different egg colors. Eggshell color is unique to every hen, depending on her kind and genetic composition. The following are the breeds that give a variety of egg colors: Araucanas breed This type of race originated in Chile. It lays around 200 gorgeous blue eggs per year Rearing: it is hard to hatch your own Araucana chicks on your yard because this breed has a lethal gene that is responsible for killing many chicks before hatching. Purchase and cost: purebred breeds vary in value depending on availability. Purebred Araucana can go up to 70dollars. Easter eggers. Easter eggers are amongst the most popular breeds to people seeking colorful eggs. It gives a variety of different colored eggs ranging from green, blue, rose, or brown to olive or cream. Rearing: this breed is tolerant of all temperaments and easily kept on the farm. Purchase and cost: readily available and can cost more than 10dollars. Welsummer Welsummer originated in Holland. This breed lay about 160 eggs per year.…

Principles of Pharmacology  (A). Discuss four stages of a drug cycle. Discuss the physiological factors involved in drug absorption and drug distribution. The phases of the drug sequence comprise the following: absorption, distribution, metabolism, and secretion. The absorption process occurs when a drug goes into the bloodstream. Absorption occurs in three forms. Firstly, enteral administration is done via either the mouth or rectal injection. Secondly, a parenteral method is administered through injection. The third administration is a percutaneous method which occurs via inhalation transdermal and topical administrations. The administrations are different in how they get into the body. However, the absorption rate may be altered by the functionality of the body (Fusman & Rasheed, 2019). Distribution is affected by diverse conditions. When the site of administration and the distribution location are close, distribution will take place rapidly. However, when the two sites are far apart, distribution will occur at a slow rate. Barriers such as the concentration of cells in the distribution site could prevent distribution. Metabolism occurs in the liver and kidneys. Medications are converted into less active states…

Effects of probiotics on Gut Microbiome Abstract estinalMore than half of the world’s population has difficulties in digestion dairy products due to its high lactose content. Lactose-intolerance is attributed to low lactase enzyme activity. Human gastrointestinal flora is constantly receiving supplements from live bacteria or yeast. Scientific studies have proven that the digestive system benefits a lot from probiotic properties in its involvement in intestinal rehabilitation.  Probiotics enhance immune responses, improve intestinal health, and reduce serum cholesterol. A series of accumulative evidence have shown that probiotic bacteria in yogurt and fresh milk can reduce lactose-intolerance. This paper aims to review the effects of probiotics in the intestinal, which include altering the intestinal microbiome, boosting immunity, and alienating lactose-intolerance. Probiotics competitively increase adherence to the mucosa and epithelium, continuously modify the gut microbiome by communicating with the host by pattern.       Impacts of probiotics on Gut Microbiome Introduction Probiotics are living microorganisms that are offering health benefits to their host if administered in the right amounts. Several studies on probiotics indicated that there are benefits of certain probiotics when…

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