why the red blood cells lost their core

why the red blood cells lost their core

Red blood cells are also known as erythrocytes. They are cellular components of the blood. They are about a million in the vertebrate’s circulation. Their main aim in the blood is to give its color and carry oxygen, which is from lungs to body tissues. The blood cells of a grownup are smaller, round, and have biconcave shape. The battery has a bell shape ad it is flexible. Due to his flexibility, it can pass through the smaller blood vessels. The outer part of the red blood cells is covered with a membrane. The membrane consists of proteins and lipids. They usually lack the nucleus. This essay will majorly highlight why the red blood cells lost their core.

In the human body, the rest of the cells have a nucleus, but the red blood cells lack the nucleus. This reflects back from the time of evolvement of mammals. Some vertebrates such as reptiles,fish, and birds they have red types of blood with cores that don’t function. As the red blood cells do not have a nucleus, it enables them to carry more oxygen. The high transportation of the oxygen in the red blood cell helps to boost our metabolism.

The scientist has tried many times to know why mature red blood cells usually expel their nucleus. According to first study on how red blood cells drops its core, this research gives much interest on the essential steps of growth in mammalians.as was researched about red blood cells in mammals that as it comes near it maturity.it has a circular of actin which typically contracts and squeezes a section of a cell containing the nucleus. This type is known as “cell division. “Nucleus then is accepted by the macrophages (fast respond immune system). Afterward, the gene sends a response in a way that determines the squeezing of the process. However, the process is unknown.

During the use of cell culture, it was actually evidenced that blood cells go through hemoglobin synthesis. This hemoglobin synthesis leads to further loss of nuclei by the red blood cells. According to lodish, a professor of biology. He revealed that three proteins are; Rac 1, mDia2, and Rac 2.are required in the ring of actin filaments. Much of the interest was on Rac2 and Rac 1 since they were needed in a drop of nuclei in red blood cells. The two proteins are well known for their importance in creating the actin fibers in most of the blood cells. They are also critical components during cellular functions and cell division due to this the help in supporting the growth of the cells.

This process of cell culture system was drawn by using red blood cells from the embryonic liver of a mouse. (the idea of using the liver was due to the production of many cells compared to adults bone marrows). This system of cultured cells is coordinate to grow together — th first divide themselves not either four or five times before losing the nuclei. Then after losing its cores, they become undeveloped red blood cells. This was noted through the use of fluorescence assays, which enable them to note any different changes that would occur. The changes were observed until the nucleus was lost.

There was a further investigation of red blood cell formation; this was done through cell division. Whereby the daughter cells receive each half of the DNA.”According to Lodish says that during the red blood cell division, one of the daughters gets all the DNA.the interesting in this case study is that the macrophages destroy the cells.up to now, scientists are unable to investigate these cells because the cells are invisible.”